In addition to being a target of estrogen-dependent transcri...

created [InstanceEdit:9038160] Rothfels, Karen, 2018-02-23
dbId 9038158
displayName In addition to being a target of estrogen-dependent transcri...
schemaClass Summation
text In addition to being a target of estrogen-dependent transcription, the progesterone receptor (PGR) interacts directly with ER alpha after stimulation with progesterone and modulates ESR1:ESTG binding (Ballare et al, 2003; Mohammed et al, 2015). Progesterone stimulation under estrogen-rich conditions promotes the release of PGR from the chaperone complex to facilitate interaction with ESR1 (Mohammed et al, 2015; reviewed in ).
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