Unlike resolvin E3, which is biosynthesised in eosinophils o...

created [InstanceEdit:9020588] Jassal, Bijay, 2017-09-07
dbId 9020580
displayName Unlike resolvin E3, which is biosynthesised in eosinophils o...
modified [InstanceEdit:9023654] Jassal, Bijay, 2017-09-28
schemaClass Summation
text Unlike resolvin E3, which is biosynthesised in eosinophils or resident macrophages via the 15-lipoxygenase (ALOX15) pathway, resolvins E1 and E2 are biosynthesised by neutrophils via the 5-lipoxygenase pathway. In neutrophils, ALOX5 oxidises 18(S)-hydroxyeicosapentaenoic acid (18(S)-HEPE) to 5(S)-hydroperoxy-18(S)-hydroxyeicosapentaenoic acid (5(S)-Hp-18(S)-HEPE) (Tjonahen et al. 2006, Oh et al. 2012).
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