Mitochondrial trans-2-enoyl-CoA reductase (MECR aka NBRF1) i...

created [InstanceEdit:8952867] Jassal, Bijay, 2016-12-20
dbId 8952861
displayName Mitochondrial trans-2-enoyl-CoA reductase (MECR aka NBRF1) i...
schemaClass Summation
text Mitochondrial trans-2-enoyl-CoA reductase (MECR aka NBRF1) is a dimeric oxidoreductase with a preference for short and medium chain trans fatty acyl-CoA substrates and may play a role in mitochondrial fatty acid synthesis (Chen et al. 2008). MECR is able to reduce trans acyl-CoA substrates of chain length C6 to C16 in an NADPH-dependent manner (Miinalainen et al. 2003). A representative reaction described here is the reduction of trans-dec-2-enoyl-CoA (tdec2-CoA) to decanoyl-CoA (DEC-CoA).
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