FBXL18, a substrate recognition subunit of the SCF E3 ubiqui...

created [InstanceEdit:8854065] Orlic-Milacic, Marija, 2016-01-26
dbId 8854056
displayName FBXL18, a substrate recognition subunit of the SCF E3 ubiqui...
modified [InstanceEdit:8854072] Orlic-Milacic, Marija, 2016-01-26
schemaClass Summation
text FBXL18, a substrate recognition subunit of the SCF E3 ubiquitin ligase complex can bind to the FQ motif of FBXL7. The E3 ubiquitin ligase complex SCF-FBXL18 (SKP1:CUL1:RBX1:FBXL18) polyubiquitinates FBXL7 on lysine residue K109, targeting it for proteasome-mediated degradation (Liu et al. 2015).
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