FGFR2 fusions have been identified in a number of cancers, i...

created [InstanceEdit:8853075] Rothfels, Karen, 2016-01-21
dbId 8853069
displayName FGFR2 fusions have been identified in a number of cancers, i...
schemaClass Summation
text FGFR2 fusions have been identified in a number of cancers, including breast, thyroid, lung and cholangiocarcinoma (Wu et al, 2013; Seo et al, 2012; Arai et al, 2013; reviewed in Parker et al, 2014). Many of the 3' fusion partners contain dimerization domains, suggesting the fusion proteins may dimerize contstitutively independent of ligand binding, although this has not been explicitly demonstrated in all cases (Wu et al, 2013; reviewed in Parker et al, 2014).
Cite Us!