D2HDGH associated with the mitochondrial inner membrane cata...

created [InstanceEdit:880051] D'Eustachio, P, 2010-06-25
dbId 880035
displayName D2HDGH associated with the mitochondrial inner membrane cata...
modified [InstanceEdit:1181203] D'Eustachio, P, 2011-01-31
schemaClass Summation
text D2HDGH associated with the mitochondrial inner membrane catalyzes the FAD-dependent reaction of (R)-2-hydroxyglutarate to form 2-oxoglutarate (Achouri et al. 2004). D2HDGH mutations are associated with high levels of (R)-2-hydroxyglutarate in vivo and variable neurological symptoms (Struys et al. 2005; Wanders and Mooyer 1995)).
Cite Us!