Cytosolic fatty acid synthase (FAS) complex catalyzes the re...

created [InstanceEdit:77382] Joshi-Tope, G, 2003-10-23 17:11:00
dbId 77381
displayName Cytosolic fatty acid synthase (FAS) complex catalyzes the re...
modified [InstanceEdit:9865851] D'Eustachio, Peter, 2024-03-19
schemaClass Summation
text Cytosolic fatty acid synthase (FAS) complex catalyzes the reaction of acetyl-CoA with 7 malonyl-CoA and 14 NADHP + 14 H+ to form a molecule of palmitate and 7 CO2, 14 NADP+, 8 CoASH, and 6 H2O. The process proceeds via the successive condensations of malonyl groups onto the growing acyl chain,each followed by loss of CO2 and three steps of reduction (Jayakumar et al. 1995; Smith et al. 2003).
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