Reactome | eIF2B is a guanine nucleotide releasing factor that is requi...

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dbId	72730
displayName	eIF2B is a guanine nucleotide releasing factor that is requi...
literatureReference	[LiteratureReference:72727] Mechanism of the nucleotide exchange reaction in eukaryotic polypeptide chain initiation. Characterization of the guanine nucleotide exchange factor as a GTP-binding protein [LiteratureReference:72723] The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2
schemaClass	Summation
text	eIF2B is a guanine nucleotide releasing factor that is required to cause GDP release so that a new GTP molecule can bind and activate eIF2, so that it can be reused.

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