Binding of TP53 (p53) to its response elements in the promot...

created [InstanceEdit:6803384] Orlic-Milacic, Marija, 2015-10-06
dbId 6803383
displayName Binding of TP53 (p53) to its response elements in the promot...
modified [InstanceEdit:8856092] Orlic-Milacic, Marija, 2016-02-08
schemaClass Summation
text Binding of TP53 (p53) to its response elements in the promoter of the CDKN1A (p21) gene stimulates CDKN1A transcription (El-Deiry et al. 1993). Binding of ZNF385A (HZF) to the DNA binding domain of TP53 facilitates CDKN1A induction and the consequent cell cycle arrest (Das et al. 2007).
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