Reactome | Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

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Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity Show undefined attributes

author	[Person:6790293] Tsai, J [Person:6790296] Lee, JT [Person:2399703] Wang, W [Person:6790281] Zhang, J [Person:6790286] Cho, H [Person:6790310] Mamo, S [Person:6790288] Bremer, R [Person:6790306] Gillette, S [Person:6790305] Kong, J [Person:6790285] Haass, NK [Person:6790287] Sproesser, K [Person:111139] Li, L [Person:6790267] Smalley, KS [Person:6790291] Fong, D [Person:6790280] Zhu, YL [Person:6790299] Marimuthu, A [Person:6790238] Nguyen, H [Person:6790294] Lam, B [Person:6790309] Liu, J [Person:6790307] Cheung, I [Person:6790301] Rice, J [Person:6790289] Suzuki, Y [Person:6790300] Luu, C [Person:6790308] Settachatgul, C [Person:6790283] Shellooe, R [Person:6790290] Cantwell, J [Person:6790297] Kim, SH [Person:111032] Schlessinger, J [Person:6790295] Zhang, KY [Person:6790302] West, BL [Person:6790284] Powell, B [Person:6790298] Habets, G [Person:2997574] Zhang, C [Person:6790282] Ibrahim, PN [Person:201395] Hirth, P [Person:6790304] Artis, DR [Person:3215412] Herlyn, M [Person:5658261] Bollag, G
created	[InstanceEdit:6790303] Rothfels, Karen, 2015-08-10
dbId	6790292
displayName	Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
journal	Proc. Natl. Acad. Sci. U.S.A.
pages	3041-6
pubMedIdentifier	18287029
schemaClass	LiteratureReference
title	Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
url	http://www.ncbi.nlm.nih.gov/pubmed/18287029
volume	105
year	2008

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[Reaction:R-HSA-6802938] Inhibitors bind and inhibit highly active BRAF mutants

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