Interleukin-13 receptor alpha subunit (IL13RA1) binds Interl...

created [InstanceEdit:6788305] Jupe, Steve, 2015-07-20
dbId 6788349
displayName Interleukin-13 receptor alpha subunit (IL13RA1) binds Interl...
literatureReference
modified [InstanceEdit:6797572] Jupe, Steve, 2015-09-14
schemaClass Summation
text Interleukin-13 receptor alpha subunit (IL13RA1) binds Interleukin-13 (IL13) with a relatively low affinity, but when paired with Interleukin-4 receptor subunit alpha (IL4R), binds with much higher affinity (Kd = 400 pmol/L) and forms a functional IL13 receptor that is capable of signaling (Miloux et al. 1997). This type II IL13 receptor complex is also the alternative type II receptor for IL4.
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