In the absence of sufficient EYA1-4 activity, APBB1 (FE65) b...

created [InstanceEdit:5683990] Orlic-Milacic, Marija, 2015-03-17
dbId 5683989
displayName In the absence of sufficient EYA1-4 activity, APBB1 (FE65) b...
schemaClass Summation
text In the absence of sufficient EYA1-4 activity, APBB1 (FE65) binds diphosphorylated H2AFX and recruits MAPK8 (JNK1) to H2AFX. This triggers pro-apoptotic signaling and targets the affected cell for apoptosis instead of DNA repair (Cook et al. 2009).
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