MAPK pathway activation is limited by a number of negative f...

created [InstanceEdit:5674498] Rothfels, Karen, 2015-02-12
dbId 5674497
displayName MAPK pathway activation is limited by a number of negative f...
schemaClass Summation
text MAPK pathway activation is limited by a number of negative feedback loops established by MAPK-dependent phosphorylations. Known substrates of activated MAPK proteins that lie upstream in the RAF/MAPK pathway include SOS, RAF1, BRAF, and MAP2K1 (Buday et al, 1995; Dong et al, 1996; Dougherty et al, 2005; Sturm et al, 2010; Fritsche-Guenther et al, 2011; Rushworth et al, 2006; Brummer et al, 2003; Ritt et al, 2010; Catalanotti et al, 2009)
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