SESN1, SESN2 and possibly SESN3 are able to bind the AMPK co...

created [InstanceEdit:5632351] Orlic-Milacic, Marija, 2014-10-28
dbId 5632350
displayName SESN1, SESN2 and possibly SESN3 are able to bind the AMPK co...
modified [InstanceEdit:8855999] Orlic-Milacic, Marija, 2016-02-08
schemaClass Summation
text SESN1, SESN2 and possibly SESN3 are able to bind the AMPK complex and increase its catalytic activity. The exact mechanism has not been elucidated, but recent studies suggest that sestrin-bound AMPK is resistant to inactivation through AKT-induced dephosphorylation (Budanov and Karin 2008, Sanli et al. 2012, Cam et al. 2014).
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