GLI2 interacts directly with beta-TrCP and is polyubiquitina...

created [InstanceEdit:5610662] Rothfels, Karen, 2014-07-22
dbId 5610661
displayName GLI2 interacts directly with beta-TrCP and is polyubiquitina...
schemaClass Summation
text GLI2 interacts directly with beta-TrCP and is polyubiquitinated in a phosphorylation-dependent manner. Binding and ubiquitination by beta-TrCP depends on 2 motifs located in the region of GLI2 phosphorylated by PKA, CK1 and GSK3 (Pan et al, 2006).
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