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Young, SN
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[InstanceEdit:5364231] Shamovsky, V, 2014-04-21
dbId
5364098
displayName
Young, SN
firstname
Samuel N
initial
SN
publications
[LiteratureReference:9697389] Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
[LiteratureReference:9820400] Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
[LiteratureReference:9698712] Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop
[LiteratureReference:9686472] Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
[LiteratureReference:9820389] Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling
[LiteratureReference:9687627] Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL
[LiteratureReference:9686475] The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis
[LiteratureReference:9707869] Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity
[LiteratureReference:9697415] Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3
[LiteratureReference:9686453] Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
[LiteratureReference:5364089] The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
[LiteratureReference:9697417] MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
[LiteratureReference:9697409] Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
schemaClass
Person
surname
Young
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