The latent endonuclease activity of MLH1:PMS2 (MutLalpha) is...

created [InstanceEdit:5358925] May, Bruce, 2014-04-05
dbId 5358929
displayName The latent endonuclease activity of MLH1:PMS2 (MutLalpha) is...
schemaClass Summation
text The latent endonuclease activity of MLH1:PMS2 (MutLalpha) is activated by interaction with MSH2:MSH3 (MutSbeta) (Zhang et al. 2005, and inferred from activation of MLH1:PMS2 by MSH2:MSH6). MLH1:PMS2 makes a nick in the strand of DNA that will be repaired (Kadyrov et al. 2006).
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