After binding a mismatch, the MSH2:MSH3 (MutSbeta) heterodim...

created [InstanceEdit:5358925] May, Bruce, 2014-04-05
dbId 5358922
displayName After binding a mismatch, the MSH2:MSH3 (MutSbeta) heterodim...
modified [InstanceEdit:5575578] May, Bruce, 2014-05-24
schemaClass Summation
text After binding a mismatch, the MSH2:MSH3 (MutSbeta) heterodimer exchanges ADP for ATP, which changes the conformation of MSH2:MSH3 to a sliding clamp or molecular switch able to diffuse in one direction along duplex DNA (Gu et al. 1998, Zhang et al. 2005, and inferred from MSH2:MSH6).
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