Reactome | Vav family members are guanine nucleotide exchange factors (...

Schema > Summation > Entries

created	[InstanceEdit:442288] Jupe, S, 2009-09-24
dbId	442297
displayName	Vav family members are guanine nucleotide exchange factors (...
literatureReference	[LiteratureReference:389268] Vav-family proteins in T-cell signalling [LiteratureReference:389291] Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product [LiteratureReference:389302] Lck regulates Vav activation of members of the Rho family of GTPases [LiteratureReference:870195] Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3
modified	[InstanceEdit:870198] Jupe, S, 2010-06-02
schemaClass	Summation
text	Vav family members are guanine nucleotide exchange factors (GEFs) for Rho-family GTPases. Vav1 is a GEF for Rac1, Rac2 and RhoG, and possibly RhoA and Cdc42

(summation)

Cite Us!