The Lsm1-7 complex forms a heptameric ring that binds the 3'...

created [InstanceEdit:429836] May, B, 2009-07-23
dbId 429948
displayName The Lsm1-7 complex forms a heptameric ring that binds the 3'...
modified [InstanceEdit:432732] May, B, 2009-08-15
schemaClass Summation
text The Lsm1-7 complex forms a heptameric ring that binds the 3' oligoadenylated ends of mRNAs that have been deadenylated. The bound Lsm1-7 may prevent access of the exosome (a 3' to 5' exonuclease) to the 3' end and thereby direct the mRNA to the 5' to 3' exonuclease pathway. The yeast Lsm1-7 complex has a preference for oligoadenylated RNA compared to polyadenylated RNA, however other determinants of binding by Lsm1-7 are unknown.
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