Reactome | Monoacylglycerol lipase (MAGL) is a key enzyme in the hydrol...

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created	[InstanceEdit:426435] Jupe, S, 2009-06-16
dbId	426423
displayName	Monoacylglycerol lipase (MAGL) is a key enzyme in the hydrol...
literatureReference	[LiteratureReference:426428] Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus [LiteratureReference:426413] Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene
schemaClass	Summation
text	Monoacylglycerol lipase (MAGL) is a key enzyme in the hydrolysis of the endocannabinoid 2-arachidonoylglycerol to arachidonate and glycerol. In adipocytes MAGL and hormone-sensitive lipase (LIPE) hydrolyze intracellular triglyceride stores. MAGL may also complement lipoprotein lipase (LPL) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides.

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