In the pancreatic beta cell, alpha2 adrenergic receptors are...

created [InstanceEdit:400084] May, B, 2009-03-24 01:57:51
dbId 400087
displayName In the pancreatic beta cell, alpha2 adrenergic receptors are...
schemaClass Summation
text In the pancreatic beta cell, alpha2 adrenergic receptors are coupled to Gi and Go heterotrimeric G-proteins. Binding of adrenaline or noradrenaline by the alpha2 adrenergic receptor acts through protein-protein interaction to stimulate the Gi alpha subunit or Go alpha subunit in heterotrimeric G-protein complexes to exchange GDP for GTP. The particular G alpha subunits have been identified in mice as Gi alpha1, Gi alpha 2, and Go alpha2.
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