While binding of the PRC1.4 complex to the H3K27Me3 mark on ...

created [InstanceEdit:3772120] Orlic-Milacic, M, 2013-06-24
dbId 3772119
displayName While binding of the PRC1.4 complex to the H3K27Me3 mark on ...
modified [InstanceEdit:9645184] Orlic-Milacic, Marija, 2019-05-06
schemaClass Summation
text While binding of the PRC1.4 complex to the H3K27Me3 mark on the promoter of p16INK4A inhibits p16INK4A transcription (Dietrich et al. 2007, Agherbi et al. 2009), KDM6B-mediated demethylation of lysine 28 of histone HIST1H3A (the removal of H3K27Me3 mark) stimulates p16INK4A transcription (Agger et al. 2009, Barradas et al. 2009).
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