Reactome | histone H3K27me2/H3K27me3 demethylase activity of KDM6B:Fe2+ [nucleoplasm]

Schema > CatalystActivity > Entries

activity	[GO_MolecularFunction:528741] histone H3K27me2/H3K27me3 demethylase activity
catalyzedEvent	[Reaction:R-HSA-9822914] KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) - Homo sapiens [Reaction:R-HSA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Homo sapiens
created	[InstanceEdit:3222594] Orlic-Milacic, M, 2013-03-25
dbId	3222588
displayName	histone H3K27me2/H3K27me3 demethylase activity of KDM6B:Fe2+ [nucleoplasm]
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
physicalEntity	[Complex:R-HSA-3222589] KDM6B:Fe2+ [nucleoplasm]
schemaClass	CatalystActivity

(catalystActivity)

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