MMADHC (Methylmalonic aciduria and homocystinuria type D pro...

created [InstanceEdit:3149561] Jassal, Bijay, 2013-02-18
dbId 3149562
displayName MMADHC (Methylmalonic aciduria and homocystinuria type D pro...
modified [InstanceEdit:9908940] D'Eustachio, Peter, 2024-04-24
schemaClass Summation
text MMADHC (Methylmalonic aciduria and homocystinuria type D protein) has sequence homology with a bacterial ATP binding cassette transporter and contains a putative cobalamin binding motif and a putative mitochondrial targeting sequence. It is required for cob(II)alamin (B12r) uptake by mitochondria (Stucki et al. 2012, Coelho et al. 2008), whereupon the complex of the two proteins dissociates, but the actual mechanism of transport into the mitochondrion is unknown (Banerjee et al. 2021).
Cite Us!