PIP2-binding AKT1 E17K mutants are anchored to the plasma m...

created [InstanceEdit:2243934] Orlic-Milacic, M, 2012-05-09
dbId 2243939
displayName PIP2-binding AKT1 E17K mutants are anchored to the plasma m...
modified [InstanceEdit:2422425] Orlic-Milacic, M, 2012-07-18
schemaClass Summation
text PIP2-binding AKT1 E17K mutants are anchored to the plasma membrane in the absence of PI3K activity and are constitutively phosphorylated on serine S473, presumably by the TORC2 complex (Carpten et al. 2007, Landgraf et al. 2008).
Cite Us!