Reactome | Nuclear Export by Exportin-5. The pre-microRNA is bound by t...

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created	[InstanceEdit:209664] Gopinathrao, G, 2008-01-02 20:43:42
dbId	209657
displayName	Nuclear Export by Exportin-5. The pre-microRNA is bound by t...
literatureReference	[LiteratureReference:203875] Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs [LiteratureReference:209665] Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs [LiteratureReference:209654] Nuclear export of microRNA precursors
modified	[InstanceEdit:432341] May, B, 2009-08-14
schemaClass	Summation
text	Nuclear Export by Exportin-5. The pre-microRNA is bound by the Exportin-5:RanGTP complex in the nucleus and the complex is translocated through the nuclear pore into the cytoplasm. In the process GTP is hydrolyzed to GDP.

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