Reactome | metallocarboxypeptidase activity of ACE2(18-805):Zn2+ dimer [plasma membrane]

Schema > CatalystActivity > Entries

activity	[GO_MolecularFunction:8516] metallocarboxypeptidase activity
catalyzedEvent	[Reaction:R-HSA-9944488] ACE2:Zn2+ cleaves 1-Ala-AGT(25-32) to yield Alamandine (1-Ala-AGT(25-31) - Homo sapiens [Reaction:R-HSA-2022379] ACE2(18-805):Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(25-31) (Angiotensin-(1-7)) - Homo sapiens [Reaction:R-HSA-2022378] ACE2(18-805):Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-33) (Angiotensin-(1-9)) - Homo sapiens
created	[InstanceEdit:2022406] May, B, 2011-11-29
dbId	2022376
displayName	metallocarboxypeptidase activity of ACE2(18-805):Zn2+ dimer [plasma membrane]
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
physicalEntity	[Complex:R-HSA-9856101] ACE2(18-805):Zn2+ dimer [plasma membrane]
schemaClass	CatalystActivity

(catalystActivity)