AKT inhibits DNA binding of NUR77 and inhibits its pro-apopt...

created [InstanceEdit:199866] Jassal, B, 2007-07-12 14:41:47
dbId 199824
displayName AKT inhibits DNA binding of NUR77 and inhibits its pro-apopt...
modified [InstanceEdit:1366599] Orlic-Milacic, Marija, 2011-06-23
schemaClass Summation
text AKT inhibits DNA binding of NUR77 and inhibits its pro-apoptotic function (PMID 11438550). However, the relevance of AKT for NUR77 phosphorylation has recently been questioned: according to recent work, NUR77 is phosphorylated by RSK (and MSK) rather than by AKT (PMID 16223362).
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