After recruitment to activated FGFR mutants, FRS2 is believe...

created [InstanceEdit:1982076] Rothfels, K, 2011-11-09
dbId 1982078
displayName After recruitment to activated FGFR mutants, FRS2 is believe...
modified [InstanceEdit:5654388] Rothfels, Karen, 2014-12-03
schemaClass Summation
text After recruitment to activated FGFR mutants, FRS2 is believed to be phosphorylated, potentially on all 6 of the tyrosines phosphorylated by wild-type FGFRs. Phosphorylation of FRS2 by FGFR has been demonstrated in some cases (see for instance Qing, 2009; Bai, 2010; Ahmed, 2008; Raffioni, 1998) and is inferred to occur in others based on activation of downstream signaling modules (reviewed in Wesche, 2011; Turner and Grose, 2010).
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