Cytosolic 5'-nucleotidase IA catalyzes the hydrolysis of pur...

created [InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
dbId 178270
displayName Cytosolic 5'-nucleotidase IA catalyzes the hydrolysis of pur...
modified [InstanceEdit:500123] D'Eustachio, P, 2010-01-31
schemaClass Summation
text Cytosolic 5'-nucleotidase IA catalyzes the hydrolysis of purine ribo- and deoxyribonucleoside monophosphates to nucleosides plus orthophosphate. The enzyme is allosterically activated by ADP (Hunsucker et al. 2001). The human enzyme is inferred to be a homotetramer with one Mg++ ion bound per subunit, based on its similarity to the pigeon heart enzyme (Bianchi and Spychala 2003; Sala-Newby et al. 1999; Skladanowski and Newby 1990).
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