This HIV-1 event was inferred from the corresponding human R...

created [InstanceEdit:167883] Matthews, L, 2005-11-10 00:32:37
dbId 167882
displayName This HIV-1 event was inferred from the corresponding human R...
modified [InstanceEdit:1455302] D'Eustachio, P, 2011-07-19
schemaClass Summation
text This HIV-1 event was inferred from the corresponding human RNA Poll II transcription event in Reactome. The details relevant to HIV-1 are described below. For a more detailed description of the general mechanism, see the link to the corresponding RNA Pol II transcription event below. The formation of the HIV-1 elongation complex involves Tat mediated recruitment of P-TEFb(Cyclin T1:Cdk9) to the TAR sequence (Wei et al, 1998) and P-TEFb(Cyclin T1:Cdk9) mediated phosphorylation of the RNA Pol II CTD as well as the negative transcriptional elongation factors DSIF and NELF (Herrmann, 1995; Ivanov et al. 2000; Fujinaga et al. 2004; Zhou et al., 2004).
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