MAP2K1 (also known as MEK1) phosphorylates the critical Thr2...
| created | [InstanceEdit:158672] Charalambous, M, 2005-02-04 06:50:22 |
| dbId | 158667 |
| displayName | MAP2K1 (also known as MEK1) phosphorylates the critical Thr2... |
| literatureReference | |
| modified | [InstanceEdit:5685042] Shamovsky, Veronica, 2015-03-24 |
| schemaClass | Summation |
| text |
MAP2K1 (also known as MEK1) phosphorylates the critical Thr202 and Tyr204 on MAPK3 (ERK1), converting two ATP to ADP. Phosphorylation of MAPK3 activates its kinase activity. MAP2K1 activation requires the phosphorylation of two serine residues (S218 and S222) in the activation loop. |
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