Reactome | metalloendopeptidase activity of ADAM17 [plasma membrane]

Schema > CatalystActivity > Entries

activity	[GO_MolecularFunction:1791] metalloendopeptidase activity
catalyzedEvent	[Reaction:R-HSA-1251992] Cleavage of P-ERBB4jmA isoforms by ADAM17 - Homo sapiens [Reaction:R-HSA-3371385] TNF-? is cleaved by ADAM17 (TACE) - Homo sapiens [Reaction:R-NUL-2063915] ADAM17 cleaves Notch1 at S2 - Mus musculus
created	[InstanceEdit:1251989] Orlic-Milacic, Marija, 2011-04-26
dbId	1251983
displayName	metalloendopeptidase activity of ADAM17 [plasma membrane]
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
physicalEntity	[Complex:R-HSA-1251963] ADAM17 [plasma membrane]
schemaClass	CatalystActivity

(catalystActivity)

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