Reactome | non-membrane spanning protein tyrosine phosphatase activity of EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane]

Schema > CatalystActivity > Entries

activeUnit	[EntityWithAccessionedSequence:R-XTR-162563] PTPN11 [cytosol] - Xenopus tropicalis
activity	[GO_MolecularFunction:14178] non-membrane spanning protein tyrosine phosphatase activity
catalyzedEvent	[Reaction:R-XTR-177924] Dephosphorylation of Gab1 by SHP2 - Xenopus tropicalis [Reaction:R-XTR-177926] Dephosphorylation of PAG by SHP2 - Xenopus tropicalis [Reaction:R-XTR-177935] SHP2 dephosphorylates Tyr 992 on EGFR - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10662611
displayName	non-membrane spanning protein tyrosine phosphatase activity of EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane]
physicalEntity	[Complex:R-XTR-180269] EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane]
schemaClass	CatalystActivity

(catalystActivity)

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