Reactome | cysteine-type endopeptidase activity of active caspase-8 [cytosol]

Schema > CatalystActivity > Entries

activeUnit	[Complex:R-CFA-139950] Caspase-8 dimer [cytosol] - Canis familiaris
activity	[GO_MolecularFunction:4344] cysteine-type endopeptidase activity
catalyzedEvent	[BlackBoxEvent:R-CFA-3465448] Caspase-8 and FLIP(L) processing at DISC - Canis familiaris [Reaction:R-CFA-350319] Caspase mediated cleavage of vimentin at IDVD (259) - Canis familiaris [Reaction:R-CFA-201637] Caspase-mediated cleavage of plectin-1 - Canis familiaris [Reaction:R-CFA-139898] Caspase-8 activates BID by cleavage - Canis familiaris [BlackBoxEvent:R-CFA-5357828] RIPK1 is cleaved by CASP8 - Canis familiaris [BlackBoxEvent:R-CFA-9686930] RIPK3 is cleaved by CASP8 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10235136
displayName	cysteine-type endopeptidase activity of active caspase-8 [cytosol]
physicalEntity	[Complex:R-CFA-2562550] active caspase-8 [cytosol]
schemaClass	CatalystActivity

(catalystActivity)