Reactome | n4bp1 [cytosol]

n4bp1 [cytosol]

Stable Identifier

R-XTR-9757941

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

N4BP1, Q6DJS0

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Cytokine Signaling in Immune system (Xenopus tropicalis)
  - Signaling by Interleukins (Xenopus tropicalis)
    - Interleukin-1 family signaling (Xenopus tropicalis)
      - Interleukin-1 signaling (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
- Innate Immune System (Xenopus tropicalis)
  - Toll-like Receptor Cascades (Xenopus tropicalis)
    - Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
      - MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
    - Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
      - Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
      - Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
    - Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
      - TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
    - Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
      - MyD88-independent TLR4 cascade (Xenopus tropicalis)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
    - Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
      - MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
      - MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
    - Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
      - MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
        
        TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
        
        Regulation of NF-kappa B signaling (Xenopus tropicalis)
        
        N4BP1 binds IKBKG (Xenopus tropicalis)
        
        IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)
        
        n4bp1 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q6DJS0

Gene Names

n4bp1

Reference Genes

BioGPS Gene:448184 n4bp1

ENSEMBL:ENSXETG00000025007

KEGG:xtr:448184 n4bp1

Monarch:448184 n4bp1

NCBI Gene:448184 n4bp1

UCSC:Q6DJS0 n4bp1

Reference Transcript

RefSeq:NM_001004870.1 n4bp1

Other Identifiers

448184

GO:0001818

GO:0002376

GO:0003723

GO:0003729

GO:0003824

GO:0004445

GO:0004518

GO:0004540

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0006629

GO:0016020

GO:0016605

GO:0016787

GO:0016791

GO:0031397

GO:0032435

GO:0043130

GO:0045071

GO:0045087

GO:0045088

GO:0046856

GO:0098542

GO:0140098

Participates

as an input of

N4BP1 binds IKBKG (Xenopus tropicalis)

as a component of

IKBKG:N4BP1 [cytosol] (Xenopus tropicalis)

Other forms of this molecule

n4bp1 [cytosol]

Inferred From

N4BP1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001004870.1

ENSEMBL

ENSXETP00000016323, ENSXETG00000025007, ENSXETT00000016323

Xenbase

XB-GENE-1216138

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