Reactome | p-T,2S-SMAD2:p-T,2S-SMAD2:SMAD4 [nucleoplasm]

p-T,2S-SMAD2:p-T,2S-SMAD2:SMAD4 [nucleoplasm]

Stable Identifier

R-XTR-9736936

Type

Complex

Species

Xenopus tropicalis

Compartment

nucleoplasm

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 2 phospho-smad2 [nucleoplasm] (Xenopus tropicalis)
smad4 [nucleoplasm] (Xenopus tropicalis)

Participates

as a component of

Ub-p-T-2S-SMAD2,3:SMAD4 [nucleoplasm] (Xenopus tropicalis)
p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] (Xenopus tropicalis)

as an input of

SMURF2 binds SMAD3 phosphorylated in the linker region (Xenopus tropicalis)

as an output of

Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Xenopus tropicalis)

Inferred From

p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] (Homo sapiens)

p-T,2S-SMAD2:p-T,2S-SMAD2:SMAD4 [nucleoplasm] (Homo sapiens)

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