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About
What is Reactome ?
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Our Logo
License Agreement
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Digital Preservation
Contact us
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Table of Contents
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How do I search ?
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tgfa [extracellular region]
Stable Identifier
R-XTR-9624183
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
extracellular region
Synonyms
TGFA(40-89), A0A8J0QR21
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
Negative regulation of the PI3K/AKT network (Xenopus tropicalis)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
RAS GEFs promote RAS nucleotide exchange (Xenopus tropicalis)
RAS GEFs [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by EGFR (Xenopus tropicalis)
EGFR autophosphorylation (Xenopus tropicalis)
EGF-like ligands:EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGFR binds EGF ligand (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGFR dimerization (Xenopus tropicalis)
EGF-like ligands:EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGFR downregulation (Xenopus tropicalis)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
CBL ubiquitinates Sprouty (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Ubiquitination of stimulated EGFR (CBL:GRB2) (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGFR interacts with phospholipase C-gamma (Xenopus tropicalis)
Active PLC-gamma1 dissociates from EGFR (Xenopus tropicalis)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGFR activates PLC-gamma1 by phosphorylation (Xenopus tropicalis)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Phospholipase C-gamma1 binds to the activated EGF receptor (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
GAB1 signalosome (Xenopus tropicalis)
Activation of SHP2 through the binding to phospho-Gab1 (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Dephosphorylation of Gab1 by SHP2 (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-Y627,659-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Dephosphorylation of PAG by SHP2 (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
GAB1 phosphorylation by EGFR kinase (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
GRB2:GAB1 binds to phosphorylated EGFR (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
PI3K binds to EGF:EGFR:GRB2:GAB1 (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
SHP2 dephosphorylates Tyr 992 on EGFR (Xenopus tropicalis)
EGF-like ligands:p-5Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Phospho-EGFR (-Y1016) dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Phospho-EGFR (- Y992) [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
GRB2 events in EGFR signaling (Xenopus tropicalis)
GRB2:SOS1 complex binds to EGF:EGFR complex (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Phosphorylation of EGFR by SRC kinase (Xenopus tropicalis)
EGF-like ligands:EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
SHC1 events in EGFR signaling (Xenopus tropicalis)
GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
SHC1 phosphorylation by phosphorylated EGFR (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR:SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Vesicle-mediated transport (Xenopus tropicalis)
Membrane Trafficking (Xenopus tropicalis)
Clathrin-mediated endocytosis (Xenopus tropicalis)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Xenopus tropicalis)
CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Cargo recognition for clathrin-mediated endocytosis (Xenopus tropicalis)
Epsin family proteins bind ubiquitinated cargo (Xenopus tropicalis)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Clathrin recruits PIK3C2A (Xenopus tropicalis)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Xenopus tropicalis)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Xenopus tropicalis)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Xenopus tropicalis)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
ubiquitinated cargo [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
tgfa [extracellular region] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A8J0QR21
Gene Names
tgfa
Reference Genes
BioGPS Gene:100485434 tgfa
ENSEMBL:ENSXETG00000024911
KEGG:xtr:100485434 tgfa
Monarch:100485434 tgfa
NCBI Gene:100485434 tgfa
UCSC:A0A8J0QR21 tgfa
Reference Transcript
RefSeq:XM_002935302.3 tgfa
Participates
as a member of
EGF-like ligands [extracellular region] (Xenopus tropicalis)
Other forms of this molecule
tgfa [clathrin-coated endocytic vesicle membrane]
tgfa [ER to Golgi transport vesicle membrane]
tgfa [endoplasmic reticulum membrane]
Inferred From
TGFA(40-89) [extracellular region]
(Homo sapiens)
Cross References
RefSeq
XP_002935348.1
Xenbase
XB-GENE-852694
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