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EGF-like ligands [extracellular region]
Stable Identifier
R-XTR-9624194
Type
Set [DefinedSet]
Species
Xenopus tropicalis
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
Negative regulation of the PI3K/AKT network (Xenopus tropicalis)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
RAS GEFs promote RAS nucleotide exchange (Xenopus tropicalis)
RAS GEFs [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by EGFR (Xenopus tropicalis)
EGFR autophosphorylation (Xenopus tropicalis)
EGF-like ligands:EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGFR binds EGF ligand (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGFR dimerization (Xenopus tropicalis)
EGF-like ligands:EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGFR downregulation (Xenopus tropicalis)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
CBL ubiquitinates Sprouty (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
Ubiquitination of stimulated EGFR (CBL:GRB2) (Xenopus tropicalis)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGFR interacts with phospholipase C-gamma (Xenopus tropicalis)
Active PLC-gamma1 dissociates from EGFR (Xenopus tropicalis)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGFR activates PLC-gamma1 by phosphorylation (Xenopus tropicalis)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
Phospholipase C-gamma1 binds to the activated EGF receptor (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
GAB1 signalosome (Xenopus tropicalis)
Activation of SHP2 through the binding to phospho-Gab1 (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
Dephosphorylation of Gab1 by SHP2 (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-Y627,659-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
Dephosphorylation of PAG by SHP2 (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
GAB1 phosphorylation by EGFR kinase (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
GRB2:GAB1 binds to phosphorylated EGFR (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
PI3K binds to EGF:EGFR:GRB2:GAB1 (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
SHP2 dephosphorylates Tyr 992 on EGFR (Xenopus tropicalis)
EGF-like ligands:p-5Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Phospho-EGFR (-Y1016) dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Phospho-EGFR (- Y992) [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
GRB2 events in EGFR signaling (Xenopus tropicalis)
GRB2:SOS1 complex binds to EGF:EGFR complex (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
SHC1 events in EGFR signaling (Xenopus tropicalis)
GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
SHC1 phosphorylation by phosphorylated EGFR (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR:SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
EGF-like ligands [extracellular region] (Xenopus tropicalis)
Participants
members
egf [extracellular region]
(Xenopus tropicalis)
areg [extracellular region]
(Xenopus tropicalis)
btc [extracellular region]
(Xenopus tropicalis)
hbegf [extracellular region]
(Xenopus tropicalis)
Participates
as a component of
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:Phospho-EGFR (- Y992) [plasma membrane] (Xenopus tropicalis)
EGFR:EGF-like ligands [plasma membrane] (Xenopus tropicalis)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane] (Xenopus tropicalis)
as an input of
EGFR binds EGF ligand (Xenopus tropicalis)
Inferred From
EGF-like ligands [extracellular region]
(Homo sapiens)
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