Reactome | atp6v1a [cytosol]

atp6v1a [cytosol]

Stable Identifier

R-XTR-912602

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

ATP6V1A, Q68F94

Locations in the PathwayBrowser

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Cellular responses to stimuli (Xenopus tropicalis)

- Cellular responses to stress (Xenopus tropicalis)
  - Cellular response to starvation (Xenopus tropicalis)
    - Amino acids regulate mTORC1 (Xenopus tropicalis)
      - RRAGA,B exchanges GDP for GTP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
      - RRAGA,B hydrolyzes GTP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
      - RRAGC,D exchanges GTP for GDP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
      - RRAGC,D hydrolyzes GTP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
      - mTORC1 binds RHEB:GTP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
  - Signaling by Insulin receptor (Xenopus tropicalis)
    - Insulin receptor recycling (Xenopus tropicalis)
      - ATP6AP1 binds V-ATPase (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
      - Endosome acidification (Xenopus tropicalis)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)

Transport of small molecules (Xenopus tropicalis)

- Ion channel transport (Xenopus tropicalis)
  - ATP6AP1 binds V-ATPase (Xenopus tropicalis)
    - V-ATPase [endosome membrane] (Xenopus tropicalis)
      - ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
    - V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
      - V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
- Iron uptake and transport (Xenopus tropicalis)
  - Transferrin endocytosis and recycling (Xenopus tropicalis)
    - ATP6AP1 binds V-ATPase (Xenopus tropicalis)
      - V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
      - V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)
    - Acidification of Tf:TfR1 containing endosome (Xenopus tropicalis)
      - V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1A trimer [cytosol] (Xenopus tropicalis)
        
        atp6v1a [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q68F94

Gene Names

atp6v1a

Reference Genes

BioGPS Gene:493238 atp6v1a

ENSEMBL:ENSXETG00000009908

KEGG:xtr:493238 atp6v1a

Monarch:493238 atp6v1a

NCBI Gene:493238 atp6v1a

UCSC:Q68F94 atp6v1a

Reference Transcript

RefSeq:NM_001007511.1 atp6v1a

Other Identifiers

493238

GO:0000166

GO:0005524

GO:0005737

GO:0006811

GO:0016020

GO:0016787

GO:0016887

GO:0033180

GO:0042592

GO:0046034

GO:0046961

GO:0055085

GO:0055086

GO:1901135

GO:1902600

Participates

as a component of

ATP6V1A trimer [cytosol] (Xenopus tropicalis)

Inferred From

ATP6V1A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001007512.1

ENSEMBL

ENSXETT00000102311, ENSXETT00000021824, ENSXETP00000074754, ENSXETP00000073477, ENSXETT00000076665, ENSXETP00000021824, ENSXETG00000009908

Xenbase

XB-GENE-479548

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