Reactome | PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane]

PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane]

Stable Identifier

R-XTR-8856806

Type

Complex

Species

Xenopus tropicalis

Compartment

plasma membrane

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 2 clathrin triskelion [cytosol] (Xenopus tropicalis)
eps15 [cytosol] (Xenopus tropicalis)
FCHO1,2 dimer [cytosol] (Xenopus tropicalis)
Ghost homologue of ITSNs [cytosol] (Xenopus tropicalis)
Ghost homologue of SGIP1 [cytosol] (Xenopus tropicalis)
Homologues of AAK1 [cytosol] (Xenopus tropicalis)
NECAPs [cytosol] (Xenopus tropicalis)
x 3 p-T156 AP-2 Complex [cytosol] (Xenopus tropicalis)
PI(4,5)P2 [plasma membrane]
reps1 [cytosol] (Xenopus tropicalis)

Participates

as an input of

CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Xenopus tropicalis)
ARBB recruits GPCRs into clathrin-coated pits (Xenopus tropicalis)

as a component of

ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Xenopus tropicalis)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)

as an output of

AAK1 phosphorylates AP-2 mu subunit at T156 (Xenopus tropicalis)

Inferred From

PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)

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