Reactome | ints2 [nucleoplasm]

ints2 [nucleoplasm]

Stable Identifier

R-XTR-6807448

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

INTS2, F6UL09

Locations in the PathwayBrowser

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Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - RNA polymerase II transcribes snRNA genes (Xenopus tropicalis)
    - Integrator complex processes the 3' end of snRNA (Xenopus tropicalis)
      - Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints2 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints2 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints2 [nucleoplasm] (Xenopus tropicalis)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints2 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints2 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6UL09

Gene Names

ints2

Reference Genes

BioGPS Gene:595088 ints2

ENSEMBL:ENSXETG00000010721

Monarch:595088 ints2

NCBI Gene:595088 ints2

Reference Transcript

RefSeq:XM_018091302.2 ints2

Other Identifiers

595088

GO:0005634

GO:0016073

GO:0016180

GO:0032039

GO:0043226

Participates

as a component of

Integrator [nucleoplasm] (Xenopus tropicalis)

Inferred From

INTS2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_017946791.1

Ensembl

ENSXETP00000023464, ENSXETG00000010721, ENSXETT00000023464

Xenbase

XB-GENE-5787298

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