Reactome | SYK [cytosol]

SYK [cytosol]

Stable Identifier

R-XTR-58268

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

A0A6I8RKY0

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Cytokine Signaling in Immune system (Xenopus tropicalis)
  - FLT3 Signaling (Xenopus tropicalis)
    - FLT3 signaling through SRC family kinases (Xenopus tropicalis)
      - Active FLT3 binds to SYK (Xenopus tropicalis)
        
        SYK [cytosol] (Xenopus tropicalis)
        
        active FLT3:SYK [plasma membrane] (Xenopus tropicalis)
        
        SYK [cytosol] (Xenopus tropicalis)
  - Signaling by Interleukins (Xenopus tropicalis)
    - Interleukin-3, Interleukin-5 and GM-CSF signaling (Xenopus tropicalis)
      - Regulation of signaling by CBL (Xenopus tropicalis)
        
        CBL ubiquitinates PI3K (Xenopus tropicalis)
        
        FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks [cytosol] (Xenopus tropicalis)
        
        FYN-like kinases [cytosol] (Xenopus tropicalis)
        
        SYK [cytosol] (Xenopus tropicalis)
        
        FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Xenopus tropicalis)
        
        FYN-like kinases [cytosol] (Xenopus tropicalis)
        
        SYK [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A6I8RKY0

Reference Genes

BioGPS Gene:100486846

ENSEMBL:ENSXETG00000000807

KEGG:xtr:100486846

Monarch:100486846

NCBI Gene:100486846

UCSC:A0A6I8RKY0

Reference Transcript

RefSeq:XM_002937027.3

Other Identifiers

100486846

GO:0000166

GO:0001946

GO:0002250

GO:0002281

GO:0002283

GO:0002376

GO:0003824

GO:0004672

GO:0004713

GO:0004715

GO:0005524

GO:0005737

GO:0005829

GO:0005886

GO:0016301

GO:0016740

GO:0033630

GO:0035556

GO:0045087

GO:0050853

GO:0090050

GO:0098542

GO:0140096

Participates

as an input of

as a component of

as a candidate of

FYN-like kinases [cytosol] (Xenopus tropicalis)

Other forms of this molecule

phospho-p-Y-SYK [cytosol]

phospho-p-Y-SYK [plasma membrane]

phospho-p-6Y-SYK [cytosol]

phospho-p-Y348-SYK [cytosol]

Inferred From

SYK [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_002937073.2

ENSEMBL

ENSXETP00000082146, ENSXETG00000000807, ENSXETT00000081115

Xenbase

XB-GENE-978184