Reactome | foxo4 [nucleoplasm]

foxo4 [nucleoplasm]

Stable Identifier

R-XTR-5690183

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

FOXO4, F6RTU2

Locations in the PathwayBrowser

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Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - Generic Transcription Pathway (Xenopus tropicalis)
    - FOXO-mediated transcription (Xenopus tropicalis)
      - FOXO-mediated transcription of cell cycle genes (Xenopus tropicalis)
        
        FOXG1 binds FOXO:SMAD complexes (Xenopus tropicalis)
        
        FOXG1:FOXO3,(FOXO1,FOXO4):p-2S-SMAD2/3:SMAD4 [nucleoplasm] (Xenopus tropicalis)
        
        FOXO3,(FOXO1,FOXO4):p-2S-SMAD2/3:SMAD4 [nucleoplasm] (Xenopus tropicalis)
        
        FOXO3,(FOXO1,FOXO4) [nucleoplasm] (Xenopus tropicalis)
        
        foxo4 [nucleoplasm] (Xenopus tropicalis)
        
        FOXO3,(FOXO1,FOXO4):p-2S-SMAD2/3:SMAD4 [nucleoplasm] (Xenopus tropicalis)
        
        FOXO3,(FOXO1,FOXO4) [nucleoplasm] (Xenopus tropicalis)
        
        foxo4 [nucleoplasm] (Xenopus tropicalis)
        
        FOXO1,FOXO3,FOXO4 bind p-2S-SMAD2/3:SMAD4 (Xenopus tropicalis)
        
        FOXO1,FOXO3,FOXO4,(FOXO6) [nucleoplasm] (Xenopus tropicalis)
        
        foxo4 [nucleoplasm] (Xenopus tropicalis)
        
        FOXO1,FOXO3,FOXO4:p-2S-SMAD2/3:SMAD4 [nucleoplasm] (Xenopus tropicalis)
        
        FOXO1,FOXO3,FOXO4,(FOXO6) [nucleoplasm] (Xenopus tropicalis)
        
        foxo4 [nucleoplasm] (Xenopus tropicalis)

Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - Deubiquitination (Xenopus tropicalis)
    - Ub-specific processing proteases (Xenopus tropicalis)
      - USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Xenopus tropicalis)
        
        USP7:TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] (Xenopus tropicalis)
        
        TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] (Xenopus tropicalis)
        
        foxo4 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6RTU2

Gene Names

foxo4

Reference Genes

BioGPS Gene:100492831 foxo4

ENSEMBL:ENSXETG00000020899

KEGG:xtr:100492831 foxo4

Monarch:100492831 foxo4

NCBI Gene:100492831 foxo4

UCSC:F6RTU2 foxo4

Reference Transcript

RefSeq:XM_002934885.5 foxo4

Other Identifiers

100492831

GO:0000978

GO:0000981

GO:0001666

GO:0003677

GO:0003700

GO:0005634

GO:0005737

GO:0006355

GO:0006357

GO:0032364

GO:0043565

Participates

as a member of

as a candidate of

FOXO3,(FOXO1,FOXO4) [nucleoplasm] (Xenopus tropicalis)

Other forms of this molecule

foxo4 [nucleoplasm]

phospho-foxo4 [cytosol]

phospho-foxo4 [nucleoplasm]

Inferred From

FOXO4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_002934931.1

ENSEMBL

ENSXETT00000045155, ENSXETG00000020899, ENSXETP00000045155

Xenbase

XB-GENE-480655

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