Reactome | mrps18c [mitochondrial inner membrane]

mrps18c [mitochondrial inner membrane]

Stable Identifier

R-XTR-5368218

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

mitochondrial inner membrane

Synonyms

MRPS18C, Q28GJ7

Locations in the PathwayBrowser

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Metabolism of proteins (Xenopus tropicalis)

- Translation (Xenopus tropicalis)
  - Mitochondrial translation (Xenopus tropicalis)
    - Mitochondrial ribosome-associated quality control (Xenopus tropicalis)
      - 55S mitochondrial ribosome:non-stop mRNA binds ICT1 (MRPL58) (Xenopus tropicalis)
        
        55S ribosome:non-stop mRNA:peptidyl-tRNA at P-site:tRNA at E-site [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome:non-stop mRNA:peptidyl-tRNA at P-site:tRNA at E-site:ICT1 [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
      - Stalled 55S mitochondrial ribosome is dissociated to yield 28S subunit and 39S subunit:mRNA:peptidyl-tRNA:tRNA (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome:mRNA:peptidyl-tRNA at P site:tRNA at E site [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
    - Mitochondrial translation elongation (Xenopus tropicalis)
      - 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Xenopus tropicalis)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
    - Mitochondrial translation termination (Xenopus tropicalis)
      - 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed (Xenopus tropicalis)
        
        55S ribosome:mRNA (UAA,UAG stop codon):peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome:mRNA (UAA,UAG stop codon):tRNA [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
      - Hydrolysis of GTP and dissociation of 28S and 39S subunits (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
      - MRRF binds 55S ribosome:mRNA:tRNA (Xenopus tropicalis)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
      - MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Xenopus tropicalis)
        
        55S ribosome:mRNA (UAA,UAG stop codon):peptidyl-tRNA at P-site [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome:mRNA (UAA,UAG stop codon):peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Xenopus tropicalis)
        
        55S ribosome [mitochondrial inner membrane] (Xenopus tropicalis)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Xenopus tropicalis)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)
        
        mrps18c [mitochondrial inner membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q28GJ7

Gene Names

mrps18c

Reference Genes

BioGPS Gene:549846 mrps18c

ENSEMBL:ENSXETG00000027597

KEGG:xtr:549846 mrps18c

Monarch:549846 mrps18c

NCBI Gene:549846 mrps18c

UCSC:Q28GJ7 mrps18c

Reference Transcript

RefSeq:NM_001017092.3 mrps18c

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Xenopus tropicalis)

Inferred From

MRPS18C [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_001017092.2

Xenbase

XB-GENE-952459

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