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MRPS18C [mitochondrial inner membrane]
Stable Identifier
R-HSA-5368218
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
28S ribosomal protein S18c, mitochondrial, RT18C_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Mitochondrial translation (Homo sapiens)
Mitochondrial translation elongation (Homo sapiens)
55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
Peptide transfer from P-site to A-site (peptide bond formation) (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation initiation (Homo sapiens)
28S subunit:MTIF3 binds MTIF2:GTP, mRNA, and formylMet-tRNA (Homo sapiens)
28S ribosomal subunit:MTIF3 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit:MTIF3:MTIF2:GTP:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
39S subunit binds 28S subunit:mRNA:fMet-tRNA (Homo sapiens)
28S ribosomal subunit:MTIF3:MTIF2:GTP:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
MTIF3 binds 28S ribosomal subunit (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit:MTIF3 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation termination (Homo sapiens)
55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
Hydrolysis of GTP and dissociation of 28S and 39S subunits (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
MRRF binds 55S ribosome:mRNA:tRNA (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
MRPS18C [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y3D5 MRPS18C
Gene Names
MRPS18C, CGI-134
Chain
transit peptide:1-, chain:-142
Reference Genes
BioGPS Gene:51023 MRPS18C
COSMIC (genes):MRPS18C MRPS18C
CTD Gene:51023 MRPS18C
dbSNP Gene:51023 MRPS18C
ENSEMBL:ENSG00000163319 MRPS18C
ENSEMBL_homo_sapiens_GENE:ENSG00000163319.11 MRPS18C
HGNC:16633 MRPS18C
KEGG Gene (Homo sapiens):51023 MRPS18C
Monarch:51023 MRPS18C
NCBI Gene:51023 MRPS18C
OMIM:611983 MRPS18C
UCSC:Q9Y3D5 MRPS18C
Reference Transcript
RefSeq:NM_001297769.1 MRPS18C
RefSeq:NM_016067.3 MRPS18C
RefSeq:NM_001297770.1 MRPS18C
Other Identifiers
11724783_a_at
11724784_at
11724785_x_at
220103_PM_s_at
220103_s_at
228019_PM_s_at
228019_s_at
2734021
2734022
2734024
2734027
2734028
2734030
2734031
2734032
2734033
2734034
2734035
2734036
44697_at
51023
8096109
A_14_P200125
A_33_P3316233
GO:0003723
GO:0003735
GO:0005198
GO:0005739
GO:0005743
GO:0005763
GO:0005840
GO:0006412
GO:0032543
GO:0043226
GO:0070181
GO:0140053
GO:1990904
Hs.3385.2.A1_3p_a_at
PH_hs_0033381
TC04000459.hg
g7705629_3p_a_at
Participates
as a member of
MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)
Inferred To
mRpS18C [mitochondrial inner membrane]
(Drosophila melanogaster)
mrps-18.c [mitochondrial inner membrane]
(Caenorhabditis elegans)
mrps18c [mitochondrial inner membrane]
(Danio rerio)
MRPS18C [mitochondrial inner membrane]
(Bos taurus)
MRPS18C [mitochondrial inner membrane]
(Canis familiaris)
MRPS18C [mitochondrial inner membrane]
(Gallus gallus)
MRPS18C [mitochondrial inner membrane]
(Sus scrofa)
Mrps18c [mitochondrial inner membrane]
(Mus musculus)
Mrps18c [mitochondrial inner membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001284699.1
,
NP_057151.1
,
NP_001284698.1
OpenTargets
ENSG00000163319
GeneCards
Q9Y3D5
HPA
ENSG00000163319-MRPS18C
Ensembl
ENSP00000295491
,
ENST00000295491
,
ENSG00000163319
PRO
Q9Y3D5
Pharos - Targets
Q9Y3D5
PDB
7PNY
,
6NU2
,
7PO1
,
6ZM6
,
7PNZ
,
6ZS9
,
7PO0
,
6ZSG
,
7A5K
,
6ZM5
,
7P2E
,
8ANY
,
6RW4
,
8OIS
,
7PO3
,
6VMI
,
7PO2
,
8OIR
,
6NU3
,
7L08
,
8CSR
,
7QI5
,
6ZSC
,
3J9M
,
6ZSA
,
6ZSB
,
8CSP
,
7QI4
,
6RW5
,
8CSQ
,
8CSU
,
6ZSE
,
6VLZ
,
7PNX
,
7A5I
,
8CST
,
7A5G
,
6ZSD
,
7A5F
,
8CSS
,
7OG4
,
7QI6
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9P031 CCDC59
1
CCDC59 [nucleoplasm]
(R-HSA-5683813)
0.527
2
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