Reactome | oxt [extracellular region]

oxt [extracellular region]

Stable Identifier

R-XTR-388474

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

extracellular region

Synonyms

AVP(20-28), F6X0Y1

Locations in the PathwayBrowser

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Vesicle-mediated transport (Xenopus tropicalis)

- Membrane Trafficking (Xenopus tropicalis)
  - Clathrin-mediated endocytosis (Xenopus tropicalis)
    - CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Xenopus tropicalis)
      - CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        ARRB:ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        ARRB:ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
    - Cargo recognition for clathrin-mediated endocytosis (Xenopus tropicalis)
      - ADBRK1,2 phosphorylate AVPR2 (Xenopus tropicalis)
        
        AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
      - ARBB recruits GPCRs into clathrin-coated pits (Xenopus tropicalis)
        
        ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Xenopus tropicalis)
        
        ARRB:ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
        
        ARRB:ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
      - ARRB bind GPCRs (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
        
        ARRB:ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
    - Clathrin recruits PIK3C2A (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        ARRB:ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Xenopus tropicalis)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        ARRB:ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)
    - Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Xenopus tropicalis)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        CLASP proteins:cargo [plasma membrane] (Xenopus tropicalis)
        
        ARRB:ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        ARRB-binding GPCRs [plasma membrane] (Xenopus tropicalis)
        
        p-AVPR2:AVP(20-28) [plasma membrane] (Xenopus tropicalis)
        
        oxt [extracellular region] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6X0Y1

Gene Names

oxt

Reference Genes

BioGPS Gene:100485685 oxt

ENSEMBL:ENSXETG00000027327

KEGG:xtr:100485685 oxt

Monarch:100485685 oxt

NCBI Gene:100485685 oxt

UCSC:F6X0Y1 oxt

Reference Transcript

RefSeq:XM_002936359.2 oxt

Other Identifiers

100485685

GO:0002125

GO:0005184

GO:0005185

GO:0005576

GO:0005615

GO:0030141

GO:0035556

GO:0048018

GO:0098772

Participates

as a component of

as a member of

SLCO3A1 substrates [extracellular region] (Xenopus tropicalis)

as an input of

Other forms of this molecule

oxt [clathrin-coated endocytic vesicle membrane]

oxt [cytosol]

Inferred From

AVP(20-28) [extracellular region] (Homo sapiens)

OXT(20-28) [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_002936405.1

ENSEMBL

ENSXETT00000038991, ENSXETG00000027327, ENSXETP00000038991

Xenbase

XB-GENE-478274

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