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AVP(20-28) [extracellular region]
Stable Identifier
R-HSA-388474
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
AVP, Arg vasopressin, RecName: Full=Vasopressin-neurophysin 2-copeptin; AltName: Full=AVP-NPII; Contains: RecName: Full=Arg-vasopressin; Contains: RecName: Full=Neurophysin 2; AltName: Full=Neurophysin-II; Contains: RecName: Full=Copeptin; Flags: Precursor;
GN Name=AVP; Synonyms=ARVP, VP;
OS Homo sapiens, NEU2_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Circadian Clock (Homo sapiens)
BMAL1:CLOCK,NPAS2 activates circadian gene expression (Homo sapiens)
Expression of AVP (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
AVPR1A,B:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
AVPR1A,B:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
AVPR1A,B:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
AVPR1A,B:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
AVPR1A,B:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Vasopressin-like receptors (Homo sapiens)
AVP(20-28) binds AVPR1A,B (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
AVPR1A,B:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
AVP(20-28) binds AVPR2 (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Aquaporin-mediated transport (Homo sapiens)
Vasopressin regulates renal water homeostasis via Aquaporins (Homo sapiens)
AVP(20-28) binds AVPR2 (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
AVP:AVPR2 Complex binds inactive heterotrimeric G(s) complex (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Homo sapiens)
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
AVPR2:AVP:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of organic anions (Homo sapiens)
SLCO3A1 isoform 1 has abroad substrate specificity (Homo sapiens)
SLCO3A1 substrates [extracellular region] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
BAR domain proteins recruit dynamin (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
ADBRK1,2 phosphorylate AVPR2 (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
ARBB recruits GPCRs into clathrin-coated pits (Homo sapiens)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
ARRB bind GPCRs (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Clathrin recruits PIK3C2A (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
Endophilins recruit synaptojanins to the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
SNX9 recruits components of the actin polymerizing machinery (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVP(20-28) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01185 AVP
Gene Names
AVP, ARVP, VP
Chain
signal peptide:1-19, peptide:20-28, chain:32-124, peptide:126-164
Reference Genes
BioGPS Gene:551 AVP
COSMIC (genes):AVP AVP
CTD Gene:551 AVP
dbSNP Gene:551 AVP
ENSEMBL:ENSG00000101200 AVP
HGNC:894 AVP
KEGG:hsa:551 AVP
Monarch:551 AVP
NCBI Gene:551 AVP
OMIM:192340 AVP
UCSC:P01185 AVP
Reference Transcript
RefSeq:NM_000490.4 AVP
RefSeq:XM_011529267.1 AVP
Other Identifiers
11732028_at
16916638
207848_PM_at
207848_at
34020_at
3895225
3895226
3895227
3895228
551
8064575
A_23_P109133
GE57806
GO:0002125
GO:0003013
GO:0003084
GO:0003824
GO:0004672
GO:0005102
GO:0005179
GO:0005184
GO:0005185
GO:0005515
GO:0005576
GO:0005615
GO:0005829
GO:0006091
GO:0006833
GO:0007165
GO:0007204
GO:0007267
GO:0007621
GO:0007625
GO:0007626
GO:0008284
GO:0010628
GO:0014049
GO:0014070
GO:0016740
GO:0022414
GO:0023052
GO:0030141
GO:0030307
GO:0030425
GO:0030669
GO:0031394
GO:0031410
GO:0031894
GO:0031895
GO:0032849
GO:0033574
GO:0035094
GO:0035176
GO:0035556
GO:0042310
GO:0042711
GO:0043027
GO:0043066
GO:0043226
GO:0045471
GO:0045907
GO:0046718
GO:0048018
GO:0050891
GO:0051970
GO:0098772
GO:0098992
GO:0140096
HMNXSV003016839
ILMN_1811443
TC20000567.hg
TC20001386.hg
X62891_s_at
g13259532_3p_at
Participates
as a component of
p-AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVPR2:AVP(20-28) [plasma membrane] (Homo sapiens)
AVPR1A,B:AVP(20-28) [plasma membrane] (Homo sapiens)
as an output of
Expression of AVP (Homo sapiens)
as a member of
SLCO3A1 substrates [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
as an input of
AVP(20-28) binds AVPR2 (Homo sapiens)
AVP(20-28) binds AVPR1A,B (Homo sapiens)
Other forms of this molecule
AVP(20-28) [cytosol]
AVP E47del [extracellular region]
AVP P7L [extracellular region]
AVP C67* [extracellular region]
AVP V67A [extracellular region]
AVP A1T [extracellular region]
AVP Y2H [extracellular region]
AVP G23R [extracellular region]
AVP(20-28) [clathrin-coated endocytic vesicle membrane]
Inferred To
Homologues of AVP(20-28) [extracellular region]
(Danio rerio)
AVP [extracellular region]
(Bos taurus)
AVP [extracellular region]
(Canis familiaris)
AVP [extracellular region]
(Sus scrofa)
oxt [extracellular region]
(Danio rerio)
oxt [extracellular region]
(Xenopus tropicalis)
OXT [extracellular region]
(Gallus gallus)
Avp [extracellular region]
(Mus musculus)
Avp [extracellular region]
(Rattus norvegicus)
avp [extracellular region]
(Danio rerio)
Cross References
RefSeq
XP_011527569.1
,
NP_000481.2
OpenTargets
ENSG00000101200
ENSEMBL
ENSP00000369647
,
ENST00000380293
HPA
ENSG00000101200-AVP
PRO
P01185
Pharos - Targets
P01185
Orphanet
AVP
GlyGen
P01185
PDB
7BB6
,
7KH0
,
7DW9
,
7BB7
,
7R0C
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43741 PRKAB2
2
PRKAB2 [cytosol]
(R-HSA-200413)
PRKAB2 [nucleoplasm]
(R-HSA-164096)
0.556
3
UniProt:P15848 ARSB
12
ARSB [azurophil granule lumen]
(R-HSA-6798774)
ARSB [extracellular region]
(R-HSA-6806236)
ARSB [ficolin-1-rich granule lumen]
(R-HSA-6800887)
ARSB [endoplasmic reticulum lumen]
(R-HSA-1614331)
OxA-ARSB [endoplasmic reticulum lumen]
(R-HSA-1614325)
OxA-ARSB [lysosomal lumen]
(R-HSA-1606837)
ARSB H393P [lysosomal lumen]
(R-HSA-5649492)
ARSB R95Q [lysosomal lumen]
(R-HSA-2314614)
ARSB G144R [lysosomal lumen]
(R-HSA-2314612)
ARSB P116H [lysosomal lumen]
(R-HSA-2314619)
ARSB C117R [lysosomal lumen]
(R-HSA-2314618)
ARSB Y86del [lysosomal lumen]
(R-HSA-2314606)
0.527
2
UniProt:Q6P9A2 GALNT18
1
GALNT18 [Golgi membrane]
(R-HSA-913685)
0.527
2
UniProt:P42773 CDKN2C
1
CDKN2C [cytosol]
(R-HSA-182572)
0.527
2
UniProt:Q13617 CUL2
3
CUL2 [cytosol]
(R-HSA-416982)
CUL2 [nucleoplasm]
(R-HSA-1234126)
G76-NEDD8-K689-CUL2 [cytosol]
(R-HSA-8952511)
0.527
2
UniProt:O95260 ATE1
0.527
2
UniProt:Q5TEU4 NDUFAF5
1
NDUFAF5 [mitochondrial inner membrane]
(R-HSA-5689127)
0.527
2
UniProt:Q92743 HTRA1
1
HTRA1 [extracellular region]
(R-HSA-8855820)
0.527
2
UniProt:Q9UBX8 B4GALT6
1
B4GALT6 [Golgi membrane]
(R-HSA-1015811)
0.527
2
UniProt:Q7LGC8 CHST3
8
CHST3 Y201* [Golgi membrane]
(R-HSA-3636860)
CHST3 L286P [Golgi membrane]
(R-HSA-3636831)
CHST3 L307P [Golgi membrane]
(R-HSA-3636832)
CHST3 R222W [Golgi membrane]
(R-HSA-3636785)
CHST3 R304Q [Golgi membrane]
(R-HSA-3636788)
CHST3 L259P [Golgi membrane]
(R-HSA-3636789)
CHST3 E372K [Golgi membrane]
(R-HSA-3636822)
CHST3 [Golgi membrane]
(R-HSA-1971541)
0.527
2
UniProt:P49356 FNTB
1
FNTB [cytosol]
(R-HSA-2530482)
0.527
2
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