Reactome | t2r48 [plasma membrane]

t2r48 [plasma membrane]

Stable Identifier

R-XTR-3299608-9

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

TAS2R40, Q2AB39

Locations in the PathwayBrowser

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Sensory Perception (Xenopus tropicalis)

- Sensory perception of taste (Xenopus tropicalis)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Xenopus tropicalis)
    - Bitter compound binds bitter taste receptor (TAS2R) (Xenopus tropicalis)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Xenopus tropicalis)
        
        TAS2R (non-orphan) [plasma membrane] (Xenopus tropicalis)
        
        Homologues of TAS2R40 [plasma membrane] (Xenopus tropicalis)
        
        t2r48 [plasma membrane] (Xenopus tropicalis)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Xenopus tropicalis)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Xenopus tropicalis)
        
        TAS2R40:ligand [plasma membrane] (Xenopus tropicalis)
        
        Homologues of TAS2R40 [plasma membrane] (Xenopus tropicalis)
        
        t2r48 [plasma membrane] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by GPCR (Xenopus tropicalis)
  - GPCR downstream signalling (Xenopus tropicalis)
    - G alpha (i) signalling events (Xenopus tropicalis)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Xenopus tropicalis)
        
        TAS2Rs [plasma membrane] (Xenopus tropicalis)
        
        Homologues of TAS2R40 [plasma membrane] (Xenopus tropicalis)
        
        t2r48 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Xenopus tropicalis)
        
        TAS2Rs [plasma membrane] (Xenopus tropicalis)
        
        Homologues of TAS2R40 [plasma membrane] (Xenopus tropicalis)
        
        t2r48 [plasma membrane] (Xenopus tropicalis)
  - GPCR ligand binding (Xenopus tropicalis)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Xenopus tropicalis)
      - T2Rs bind bitter-tasting compounds (Xenopus tropicalis)
        
        TAS2Rs [plasma membrane] (Xenopus tropicalis)
        
        Homologues of TAS2R40 [plasma membrane] (Xenopus tropicalis)
        
        t2r48 [plasma membrane] (Xenopus tropicalis)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Xenopus tropicalis)
        
        TAS2Rs [plasma membrane] (Xenopus tropicalis)
        
        Homologues of TAS2R40 [plasma membrane] (Xenopus tropicalis)
        
        t2r48 [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q2AB39

Gene Names

t2r48

Reference Genes

BioGPS Gene:100335095 t2r48

ENSEMBL:ENSXETG00000046203

KEGG:xtr:100335095 t2r48

Monarch:100335095 t2r48

NCBI Gene:100335095 t2r48

UCSC:Q2AB39 t2r48

Reference Transcript

RefSeq:NM_001172031.1 t2r48

Other Identifiers

100335095

GO:0001580

GO:0004930

GO:0007165

GO:0007186

GO:0016020

GO:0033038

GO:0050877

GO:0050909

Participates

as a member of

Homologues of TAS2R40 [plasma membrane] (Xenopus tropicalis)

Other forms of this molecule

t2r48 [plasma membrane]

Inferred From

TAS2R40 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001165502.1

ENSEMBL

ENSXETT00000082983, ENSXETG00000046203, ENSXETP00000086213

Xenbase

XB-GENE-29099627